P-030 Treatment for CMV Infection in UC Patients Significantly Decreased the Colectomy Rate
نویسندگان
چکیده
منابع مشابه
Effect and safety of granulocyte-monocyte adsorption apheresis for patients with ulcerative colitis positive for cytomegalovirus in comparison with immunosuppressants.
BACKGROUND Cytomegalovirus (CMV) infection exacerbates ulcerative colitis (UC) refractory to immunosuppressive therapies (IMT). However, the underlying UC remained active in some UC patients, despite the fact that CMV-DNA in colonic mucosa became negative after antiviral therapy. Therefore, new therapeutic strategies for UC patients concomitant with CMV infection in mucosa are required. AIMS ...
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BACKGROUND/AIMS Cytomegalovirus (CMV) reactivations are frequently observed in patients with active ulcerative colitis (UC), and ganciclovir therapy is effective in patients with steroid-refractory UC. This study aimed to determine the long-term outcomes of CMV reactivation and the long-term therapeutic efficacy of ganciclovir treatment. METHODS This retrospective multicenter study included a...
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OBJECTIVES Cytomegalovirus (CMV) infections in liver transplant recipients are common and result in significant morbidity and mortality. Intravenous ganciclovir or oral valganciclovir are the standard treatment for CMV infection. The present study investigates the efficacy of oral valganciclovir in CMV infection as a preemptive treatment after liver transplantation. METHODS Between 2012 and 2...
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Cytomegalovirus (CMV) reactivation is common in patients with severe ulcerative colitis (UC), and may ref lect exacerbation of mucosal inf lammation and/or administration of immunosuppressants. The question of whether CMV is an active pathogen or 'an innocent bystander' in the exacerbation of UC remains controversial. Patients with UC exacerbated by reactivated CMV experience worse prognoses th...
متن کاملintensity of hla-a2 expression significantly decreased in occult hepatitis b infection
background occult hepatitis b infected (obi) patients cannot eradicate hepatitis b virus (hbv)-dna from their liver and peripheral blood, completely. objectives the main aim of this study was to investigate the rate of hla-a2 expression on peripheral blood mononuclear cells (pbmcs) of patients with obi. materials and methods in this experimental study, intensity of hla-a2 was measured on the pb...
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ژورنال
عنوان ژورنال: Inflammatory Bowel Diseases
سال: 2014
ISSN: 1078-0998
DOI: 10.1097/01.mib.0000456751.84152.e1